Microbiome & Health

The course will provide an introduction to the microbiome and will discuss the role of microbiome in human health. Microbiome refers to the collective community of microbes (e.g. bacteria, archaea, viruses and fungi) and the function of their genomes. The number of studies related to microbiome has grown recently, coinciding with interest from the public and media in the potential of the microbiome to affect human health. The goal of this course is to provide background on important concepts related to microbiome and methodological issues common in epidemiological studies of microbiome. Concepts related to microbial ecology, gut biogeography, relationship with nutrition and metabolism, and how various factors including life stages affect the microbiome will be covered. The course will also focus on epidemiologic methods for gut microbiome studies including a focus on study design, implementation, and analysis along with a discussion on potential threats to causal inference. The concepts and methods learned will then be applied to various topics of microbiome and health (gastrointestinal diseases, infectious diseases, cancer, diabetes, obesity and environmental health).